跳至主要内容
临床试验/CTRI/2024/10/075443
CTRI/2024/10/075443尚未招募不适用

Association of Oro-tracheal tube inserted depth with anatomi-cal parameters among infants

Jawaharlal institute of post graduate medical education and research1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2024年10月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
200
试验地点
1
主要终点
To measure the inserted depth of ET tube, nasotragal length, sternal length, foot length, thyromental length and manubriosternal junction to mental length and find out appropriate formulae for estimating the insertion depth of endotracheal tube using those parameters.

研究概览

简要总结

:  Endotracheal intubation is a common procedure done in infants and neonates requiring respiratory support. More often this procedure is done in emergency setting, where predicting data such as weight of the patient may not be easy. After intubation, it is a standard medical practice to confirm the clinically effective position of the tip of the ET tube initially by chest auscultation and later by EtCO2. Optimal Endotracheal (ET) tube positioning is important, and the ideal position is halfway between vocal cord and carina. If an ET tube is placed too high accidental extubation may occur, if placed too low then endobronchial intubation, poor ventilation, atelectasis or pneumothorax may occur. The initial clinical assessment of the appropriate intubation depth is to auscultate equal  air entry to the bilateral lungs. Nevertheless, it lacks a quantitative or qualitative change of breathing sound detected on auscultation, despite 1cm downward displacement of the ET tube tip into the main bronchus; one study indicated that up to 60% of endobronchial intubations were by equal breath sound auscultation. Thus, several methods have been reported to determine the proper ET tube depth for  intubation and the accurate ET tube tip position, such as the well-known 7-8-9 Rule, body parameters as a predictor, the manufacturer’s markings on the tube tip and sonogram. Also, a number of nomograms are available to predict this depth from external body measurements such as weight, head circumference, crown-heel or crown-rump length. However, many of these studies have their limitations.

研究设计

研究类型
Observational

入排标准

年龄范围
1.00 Day(s) 至 1.00 Year(s)(—)
性别
All

入选标准

  • Neonates and infants who undergoes an elective / emergency orotracheal intubation with tip of the ET tube in clinically effective position based on ET tube depth marker at the level of glottis.

排除标准

  • Infants with congenital anomalies of head and neck that complicate the ET tube intubation procedure are excluded.

结局指标

主要结局

To measure the inserted depth of ET tube, nasotragal length, sternal length, foot length, thyromental length and manubriosternal junction to mental length and find out appropriate formulae for estimating the insertion depth of endotracheal tube using those parameters.

时间窗: 30 minutes to 1 hour

次要结局

  • to develop a regression model to predict ET tube insertional depth using the anatomical parameters(at the time of intubation)

研究者

发起方
Jawaharlal institute of post graduate medical education and research
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Pappu Kumar Mahato

Jawaharlal Institute of Postgraduate Medical Education and Research

研究点 (1)

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