COMPARISON OF THE EFFECTS OF DEEP AND SLOW BREATHING EXERCISES AND SUBOCCIPITAL RELEASE, ADDED TO ROUTINE PHYSIOTHERAPY AND REHABILITATION, ON AUTONOMIC, MOTOR, AND COGNITIVE FUNCTIONS AND EMOTIONAL STATUS IN STROKE PATIENTS
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- Heart Rate Variability (HRV)
研究概览
简要总结
The aim of this study is to investigate the positive effects of deep, slow breathing exercises and suboccipital relaxation, when added to a routine physiotherapy and rehabilitation program, on autonomic, motor, cognitive, and emotional status functions in individuals who have experienced a stroke, and to examine their superiority compared to routine physiotherapy and rehabilitation alone.
详细描述
Deep, slow breathing exercises have been reported in the literature to positively affect lung function, balance, and gait. Studies have also shown that slow and deep breathing can improve cognitive function. Current evidence indicates that these exercises significantly enhance baroreflex function, heart rate variability (HRV), and blood pressure regulation, as well as improve sleep quality and emotional conditions such as stress, anxiety, and depression.
Suboccipital relaxation has been identified as a beneficial therapeutic approach for improving balance and gait ability in individuals with chronic stroke. Additionally, cervical mobilization has been suggested as a supportive intervention in stroke rehabilitation. Suboccipital relaxation is noteworthy due to its potential to influence the parasympathetic nervous system, which plays a key role in regulating various bodily functions, including heart rate, digestion, and stress responses. Furthermore, the combined use of cervical joint mobilization and diaphragmatic breathing in individuals with chronic stroke has been reported to improve lung function and craniovertebral angle.
Although the literature reports positive effects of deep, slow breathing exercises and suboccipital relaxation individually, these methods have primarily been studied separately. To date, no study has evaluated their combined or comparative effects in stroke rehabilitation. In this respect, the present study is both clinically and methodologically novel. It aims to generate scientific evidence for multidimensional recovery processes after stroke, provide a theoretical and practical foundation for the development of comprehensive rehabilitation protocols, and ultimately contribute to reducing the global burden of stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 84 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •First-time diagnosis of stroke
- •Presence of unilateral hemiplegia due to ischemic or hemorrhagic stroke etiology
- •Presence of hemiparesis
- •At least 3 months post-stroke
- •Having signed the informed consent form
- •Aged between 18 and 84 years
排除标准
- •Presence of active or chronic respiratory disease
- •Low heart rate (<60 bpm)
- •Known cardiac conduction disorder
- •Symptomatic carotid or vertebrobasilar stenosis
- •Severe carotid or vertebrobasilar stenosis
- •Advanced liver, kidney, heart, or lung disease
- •Diagnosed depression
- •Pregnancy
- •Severe aphasia or cognitive impairment that may interfere with the informed consent process or study procedures
- •Malignant tumors or infectious diseases
- •Presence of a pacemaker or other implanted electrical device
- •Spasticity of grade 4 or higher according to the Modified Ashworth Scale in the upper and lower extremities
- •Brunnstrom Motor Staging below stage 3 in the upper and lower extremities
- •Failure to meet the inclusion criteria
结局指标
主要结局
Heart Rate Variability (HRV)
时间窗: Baseline and after 6 weeks of intervention
Heart Rate Variability (HRV) will be measured using the Polar H10 chest strap sensor. The device is placed below the chest and transmits data via Bluetooth to the Elite HRV mobile application. The following HRV parameters will be recorded: RMSSD(Root Mean Square of Successive Differences), SDNN(Standard Deviation of Normal-to-Normal intervals), low-frequency (LF) power (ms²), and high-frequency (HF) power (ms²). RMSSD and HF reflect parasympathetic activity, while SDNN represents overall autonomic activity. LF reflects both sympathetic and parasympathetic activity but is mainly associated with sympathetic modulation. HF is influenced by respiration and increases during relaxation and deep breathing.
次要结局
- Berg Balance Scale (BBS)(Baseline and after 6 weeks of intervention)
- Motor Activity Log-28 (MAL-28)(Baseline and after 6 weeks of intervention)
- Fugl-Meyer Assessment - Upper Extremity (FMA-UE):(Baseline and after 6 weeks of intervention)
- Montreal Cognitive Assessment (MoCA):(Baseline and after 6 weeks of intervention)
- Beck Depression Inventory (BDI):(Baseline and after 6 weeks of intervention)
研究者
Bihter Aslanyurek
Associate Professor
Ankara Yildirim Beyazıt University
