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临床试验/NCT06327061
NCT06327061招募中不适用

A Social Diffusion Fatal Overdose Prevention Intervention: Assessing the Effectiveness of People Who Use Opioids as Peer Educators in Training Using & Non-using Networks on Overdose & Stigma Reduction

Johns Hopkins Bloomberg School of Public Health1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2024年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
600
试验地点
1
主要终点
Participant drug use

研究概览

简要总结

The purpose of this study is to test a social intervention focused on overdose prevention and care. In the investigators prior work, the investigators have shown that people who use opioids (PWUO) can be effective peer educators (PEs).

详细描述

The purpose of this study is to test a social intervention focused on overdose prevention and care. In the investigators prior work, the investigators have shown that people who use opioids (PWUO) can be effective peer educators (PEs). The investigators have utilized PEs for overdose prevention in interventions that have focused on training network members who use drugs to respond to an overdose. Yet, many overdoses are witnessed by people who do not use drugs. Additionally, many PWUO report using drugs at home and living with someone who does not use drugs, which highlights the importance of training non-using network members on overdose response. Based on pilot data, the investigators propose expanding an overdose peer education intervention to focus on non-using network members. The intervention seeks to prepare network members to respond to an overdose and normalize discussions about overdose prevention planning between index PWUO and non-using network members. The intervention condition consists of 3 individual sessions focused on overdose prevention and response. This condition is designed to train index study participants to be Peer Educators. In addition to the three sessions, the non-drug using network member will be offered one session. The control condition is only 1 session focused on overdose prevention and response. Both intervention and control participants will invite social network members to take part in data collection activities

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Participant)

盲法说明

Both groups receive overdose prevention training

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • self-reported illicit opioid use at least 2 times in the past two weeks;
  • age 18 and older;
  • living in the Baltimore metropolitan region;
  • willing to engage in peer education; and
  • having and willing to recruit at least one non-using network member.

排除标准

  • Participants without the cognitive ability to provide informed consent and have the physical ability to participate in in-person intervention sessions.

研究组 & 干预措施

Experimental: Peer education and network support

Experimental

During sessions 1 and 2, participants will be taught information and skills pertaining to overdose prevention and response. During the 3rd session, participants will trained to talk to their non drug using network members in overdose prevention and response.

干预措施: Network overdose prevention (Behavioral)

comparison: Standard of care of health education

Active Comparator

In one session, participants will receive the standard of care for overdose prevention.

干预措施: Standard of care health education (Behavioral)

结局指标

主要结局

Participant drug use

时间窗: 3-months

Proportion of times participants tested positive for drugs of fentanyl and xylazine using test strips in the prior 3 months.

Number of drug overdoses

时间窗: 3-months

Number of drug overdoses in prior three months

次要结局

  • Number of Network member contacts(3-months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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