Incidence of Symptomatic and Asymptomatic Influenza Among Healthcare Workers : A Multicenter Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 289
- 试验地点
- 1
- 主要终点
- Incidence of influenza cases
研究概览
简要总结
Although clinical presentation of influenza is often symptomatic, asymptomatic cases also occur. The knowledge of the incidence of asymptomatic influenza among healthcare workers is very important because of the risk of cross-transmission to hospitalized patients. The principal objective of the study is to estimate the incidence of symptomatic and asymptomatic influenza among healthcare workers in short-stay wards. The results of this study will lead to a better understanding of the burden of asymptomatic influenza among healthcare workers and might be used as an argument to increase influenza vaccine coverage among healthcare workers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Volunteer health-care workers
- •Working in the following wards: short-stay, inpatient (including ICU) and emergency
排除标准
- •Presence of influenza symptoms at enrolment
- •Programmed absence (maternity leave, vacation, etc.)
- •Administrative agents
研究组 & 干预措施
Health-care workers
Health-care workers recruited in the study will have blood sampling and naso-pharyngeal bottle-brush sampling
干预措施: Blood sampling (Biological)
Health-care workers
Health-care workers recruited in the study will have blood sampling and naso-pharyngeal bottle-brush sampling
干预措施: Nasal swab (Other)
结局指标
主要结局
Incidence of influenza cases
时间窗: 6 months after inclusion
Incidence of asymptomatic and symptomatic influenza per 1000 days at risk among healthcare workers
次要结局
- Incidence of influenza-like illness(6 months after inclusion)
- Number of sick-leave days per participating ward(6 months after inclusion)
- Stratified incidence ratios(6 months after inclusion)
- Fraction of asymptomatic influenza cases(6 months after inclusion)
- proportion of health-care workers with Influenza vaccine coverage(6 months after inclusion)