A Study to assess the Efficacy of Erector Spinae Plane Block (ESPB) for Post operative analgesia in patients undergoing laparoscopic Cholesystectomy under General Ananesthesia
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Postoperative duration of analgesia
研究概览
简要总结
The erector spinae block is achieved by injecting the local anasthetic solution between the erector spinae muscles (ilicostalis, longissimus, spinalis from lateral to medial) and transverse process. The local anesthetic diffuses into the paravertebral space through spaces between adjacent vertebrae and blocks both the dorsal and ventral branches of thoracic spinal nerves.6-7
In the current study, we will evaluate the efficacy of ESP block by using 0.25% ropivacaine in patients undergoing laparoscopic cholecystectomy under general anesthesia, in terms of postoperative duration of analgesia, intensity of pain, time to request for first rescue analgesic, total rescue analgesic consumption, hemodynamic changes and adverse effects/ complications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Double Blind Double Dummy
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age between 18 to 60 years ASA Physical Status 1 and 2 Patients with valid informed consent.
排除标准
- •BMI > 35 kg/m2 Skin infection at puncture site Severe coagulopathy Hypersensitivity to drugs CVS and Respiratory diseases Chronic Renal or liver failure Neurological or psychiatric illness.
结局指标
主要结局
Postoperative duration of analgesia
时间窗: 0 to 10
次要结局
- Postoperative intensity of pain (VAS)(Time to first rescue analgesic requirement)