The Effect of Metabolism-Boosting Beverages on 24 Hr Energy Expenditure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- To assess the effect of MBBs on REE by performing indirect calorimetry
研究概览
简要总结
The purpose of this study is to assess the effect of Metabolism-boosting Beverages (MBB) containing green tea extract with a standardized amount of epigallocatechin gallate (EGCG) and caffeine.
详细描述
The study will assess the effect of MBB's on 24 hour energy expenditure by performing indirect calorimetry, and on appetite using visual analogue scales (VAS). The planned sample size is 54 healthy male and female adults, both lean and overweight. We plan to test 6 metabolism-boosting beverages in the following order: 1) Raspberry Tea 2) Banana Shake 3) Chai Latte 4) Strawberry Shake 5) Cappuccino 6) Hot Cocoa. In the order that they are screened, each subject will be assigned to receive 1 of 6 Metabolism-boosting beverages. Each MBB will contain 90 mg EGCG and 100 mg caffeine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult males and females (age between 18 and 65)
- •BMI ≥18.5 - ≤ 40.0 kg/m2
- •Non-smokers
- •No known food allergies to wheat, gluten, soy or nuts
- •≤ 14 alcoholic beverages per week
- •No sensitivity to caffeine or green tea
- •No alcohol or caffeine on days when metabolism is tested
- •Willing and able to give informed consent
- •Not currently using appetite-affecting medications (e.g SSRIs, steroids, Ritalin)
- •Not pregnant or lactating
排除标准
- •Actively dieting
- •Chronic uncontrolled health problems (not including obesity or controlled: type-2 diabetes, hyperlipidemia, hypertension)
- •History of arrhythmia, or taking anti-arrhythmic medications (e.g. propafenone)
- •Schizophrenia, history of bipolar disorder, current Major Depressive Disorder
- •Dependence on alcohol or sedative-hypnotic drugs (e.g. benzodiazepines)
- •Cognitive impairment severe enough to preclude informed consent
- •Taking weight loss or appetite-suppressant medications
- •Taking appetite affecting medications (e.g. SSRIs, steroids, Ritalin)
- •Food allergies to wheat, gluten, soy, or nuts
- •Sensitivity to caffeine or green tea
结局指标
主要结局
To assess the effect of MBBs on REE by performing indirect calorimetry
时间窗: 30, 60, 90, and 120 minutes
次要结局
- To assess the effect of MBBs on appetite via visual analogue scales(30, 60, 90, and 120 minutes)