NCT06210230已完成不适用
Double-blind and Placebo-controlled Study on Intervention Effect of Medium and Long Chain Fatty Acid Triglyceride on Glycolipid Homeostasis in Patients With Metabolic Syndrome and Mechanisms
Zhejiang University1 个研究点 分布在 1 个国家目标入组 240 人开始时间: 2023年5月22日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Change in blood lipids from baseline
研究概览
简要总结
Double-blind and placebo-controlled study on intervention effect of medium and long chain fatty acid triglyceride on glycolipid homeostasis in patients with metabolic syndrome and mechanisms
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed metabolic syndrome according to IDF diagnostic criteria;
- •Rarely eating out of home;
- •Aged between 40 and 70 years.
排除标准
- •Breastfeeding or pregnancy;
- •History of heart disease, coronary heart disease, stroke, cerebral infarction, viral liver disease (hepatitis A, hepatitis B, etc.), chronic kidney disease (GFR<60 ml/min) or cancer;
- •Diabetic ketoacidosis or hyperketosis;
- •Drug use has changed in the past six months;
- •Taking insulin;
- •Used MLCT edible oil in the past six months;
- •Have participated in other clinical trials in the last three months.
结局指标
主要结局
Change in blood lipids from baseline
时间窗: 6 months
The investigators will measure Triglycerides (TG), total cholesterol (TC), LDL-C, and HDL-C levels in blood samples before and after treatment.
Change in blood glucose from baseline
时间窗: 6 months
The investigators will measure HbA1c and fasting plasma glucose levels in blood samples before and after treatment.
次要结局
未报告次要终点
研究者
Yu Zhang
Professor
Zhejiang University
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
Brain Responses to Short-Chain Fatty Acid InterventionStressHealthy VolunteersNCT06546683Universitaire Ziekenhuizen KU Leuven32
已完成
不适用
Multi-Center Study to Determine the Role of Fatty Acids in Serum in Preventing Retinopathy of Prematurity (MDM)Ophthalmological DisorderNCT03201588Göteborg University210
已完成
不适用
Effect of Short-chain Fatty Acids on Aerobic EnduranceAerobic EnduranceMetabolismNCT06054607United States Army Research Institute of Environmental Medicine21
已完成
不适用
The Effect of Plant Sterols on the Blood Lipid Profile of Subjects With and at High Risk of Type 2 Diabetes MellitusVascular DiseasesDiabetes MellitusHypercholesterolemiaNCT02288585Unilever R&D150
已完成
3 期
MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162)HypercholesterolemiaNCT01154036Organon and Co1,547