Echo-Cardiographic Assessment of Cardiovascular Characteristics During Pregnancy and Postpartum Periods
试验速览
- 阶段
- 不适用
- 入组人数
- 400
- 试验地点
- 1
研究概览
简要总结
The purpose of this echocardiographic study is to restudy the longitudinal changes in cardiac size and function during and after pregnancy in healthy women using relatively new parameters of systolic and diastolic function as well as classical measures of left ventricle (LV) function using contemporary echocardiographic machines.
We, the researchers at Hillel Yaffe Medical Center, will assess diastolic function and its possible relation to shortness of breath.
详细描述
A comprehensive echocardiographic study of the heart will be conducted in the first, second and third trimesters of pregnancy and 3 months postpartum.
Determination of left ventricular dimensions, transvalvular Doppler flow, ejection fraction, stroke volume, cardiac output, pulmonary vein flow, tissue Doppler, flow propagation, global and segmental strain parameters, timing of peak strain and various parameters of diastolic function will be obtained.
From these data normal values for various stages of pregnancy will be determined as well as range for changes expected during longitudinal follow-up will be determined.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy women
- •First trimester of a normal pregnancy
- •Normal baseline echocardiogram
排除标准
- •Pregnancy with more than one fetus.
- •Any hemodynamically significant cardiac condition
- •Any known systemic disease
- •Poor quality echocardiogram