The Comparison of the Cardiovascular Effects of Remifentanil and Nitroprusside for Controlled Hypotension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Cardiac index
研究概览
简要总结
The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent endoscopic sinus surgery
排除标准
- •patient who took any drug to influence this study
- •patient with cardiovascular disease, renal disease or liver disease
研究组 & 干预措施
nitroprusside
After induction of anesthesia, controlled hypotension was induced with continuous infusion of nitroprusside. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK).
干预措施: nitroprusside (Drug)
remifentanil
After induction of anesthesia, controlled hypotension was induced with continuous infusion of remifentanil. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK).
干预措施: remifentanil (Drug)
结局指标
主要结局
Cardiac index
时间窗: Cardiac index was continuously measured during controlled hypotension, an average of 90 min
Cardiac index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of cardiac index during controlled hypotension was compared with baseline value.
次要结局
- Total peripheral resistance index(Total peripheral resistance index was continuously measured during controlled hypotension, an average of 90 min)
研究者
Hyun Jung Kim
Assistant professor
Jeju National University School of Medicine