To Investigate the Effect of Plasticizers on the Pregnancy in Vitro Fertilization Cycles
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Phthalate of urine
研究概览
简要总结
To investigate the effect of Plasticizer metabolites concentration on the in vitro fertilization outcomes
详细描述
This study was conducted in a medical center in southern Taiwan. 80 infertile female patients, aged 30 to 40 years old with normal ovarian function, receiving IVF treatment in the infertility outpatient were enrolled in this study. The participates were divided into two groups: successful pregnancy in the IVF cycle (n = 40) and non-pregnancy in the IVF cycle (n = 40). After getting the consent of the patients, we plan to do a questionnaire survey. Additionally, environmental dust and urine were sampled and analyzed the concentration of plasticizers metabolites.The aim of this study is to investigate the effect of Plasticizer metabolites concentration on the in vitro fertilization outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 30 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Infertile women undergoing in vitro fertilization cycles
- •Normal ovarian reserve (AMH > 1.0 and AFC ≧ 5)
排除标准
- •Daily homestay time > 12 hrs
- •Diminished ovarian reserve (AMH ≦ 1.0 or AFC<5)
- •Oophorectomy
- •Gynecologic cancer patients
- •Severe male infertility
结局指标
主要结局
Phthalate of urine
时间窗: through study completion, an average of 1 year
Phthalate metabolites concentrations
次要结局
- Phthalate of environmental dust(through study completion, an average of 1 year)
研究者
Li-Te Lin
Dr.
Kaohsiung Veterans General Hospital.