Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 137
- 试验地点
- 1
- 主要终点
- Susceptability Changes in Streptococcus Pneumoniae Distal to the Site of Instillation
研究概览
简要总结
Topical Treatment of Bacterial Conjunctivitis and its Effect on Microbial Flora
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 盲法
- Single
入排标准
- 年龄范围
- 1 Year 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients from 1 to 13 years of age that have diagnosis of bacterial conjunctivitis in either or both eyes (for < 3 days duration) based on clinical observation; matched healthy controls
排除标准
- •Cannot have had bacterial conjunctivitis symptoms as reported by parent for > 2 days
研究组 & 干预措施
Infected Patient treated with Vigamox
Conjunctivitis-Infected Patient receiving Vigamox 0.5% in both eyes three times daily for 7 days.
干预措施: VIGAMOX (Drug)
结局指标
主要结局
Susceptability Changes in Streptococcus Pneumoniae Distal to the Site of Instillation
时间窗: Day 0 and Day 42
Susceptibility change refers to a change in vulnerability of a specified bacterial strain to antibiotic treatment. Susceptibility was assessed by broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI). 0% = zero isolates were resistant to antibiotic 100% = all isolates were resistant to antibiotic
Susceptability Changes in Staphylococcus Aureus Distal to the Site of Instillation
时间窗: Day 0, Day 42
Susceptibility change refers to a change in vulnerability of a specified bacterial strain to antibiotic treatment. Susceptibility was assessed by broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI). 0% = zero isolates were resistant to antibiotic 100% = all isolates were resistant to antibiotic
Susceptability Changes in Haemophilus Influenzae Distal to the Site of Instillation
时间窗: Day 0, Day 42
Susceptibility change refers to a change in vulnerability of a specified bacterial strain to antibiotic treatment. Susceptibility was assessed by broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI). 0% = zero isolates were resistant to antibiotic 100% = all isolates were resistant to antibiotic
次要结局
未报告次要终点