Hypomagnesemia in Critically ill Sepsis Patients in ICU: A Hospital Based Cross- sectional study

This is a hospital-based cross-sectional observational study designed to evaluate the prevalence and clinical impact of hypomagnesemia in critically ill sepsis patients admitted to the intensive care unit ICU at Sharda Hospital Greater Noida. The study will be conducted from June 2025 to December 2026 and will include 100 adult patients diagnosed with sepsis based on Sepsis 3 criteria and admitted to the multidisciplinary ICU. Patients under 18 years of age those with prior documented hypomagnesemia or those receiving magnesium supplementation before admission will be excluded.

Serum magnesium levels will be measured within 24 hours of sepsis diagnosis and monitored every 48 to 72 hours during the ICU stay. Hypomagnesemia will be defined as serum magnesium less than 1.6 milligrams per deciliter. Additional parameters such as serum potassium levels SOFA score ventilator requirements duration of ICU stay and patient outcomes including mortality will be recorded. The study will also identify underlying causes of hypomagnesemia including gastrointestinal losses renal dysfunction and drug-induced losses.

Data will be analyzed using SPSS software. Descriptive and inferential statistics will be used to determine prevalence associations and correlations. The study aims to highlight the clinical relevance of magnesium monitoring in ICU sepsis patients to improve patient management outcomes and standard care protocols. There is limited Indian data on this topic and the findings of this study may help bridge this gap and guide further research in critical care electrolyte management.