Effects of Progressive Resistance Exercise in Akinetic-rigid Parkinson's Disease Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Static posturography through the centre of pressures measurements (CoP).
研究概览
简要总结
The aim of this randomized controlled trial was to assess the impact of progressive resistance exercise (PRE) in PD patients with akinesia and rigidity (AR-subtype). The investigators hypothesized the intervention would have a beneficial effect on the study outcomes.
详细描述
Twenty-eight patients with PD AR-type of both sexes, were recruited for this trial. Each participant were assigned randomly to either intervention (N=13) or control (N=15) group.
The intervention group participated in sixteen PRE training sessions for eight weeks: two sessions per week on non-consecutive days, sixty-seventy min each one. The control group followed their usual weekly physical activity routine.
All patients underwent antrophometrical and neuromuscular function assessment (CoP measurements -primary outcomes- and the Ten-Meters Walk Test -TMWT- -secondary outcomes-). In addition, they were asked to provide ratings for the Spanish validated versions of the the Freezing of Gait Questionnaire (FOG-Q, 6-item version) -secondary outcomes-, the 39-item Parkinson ́s disease Questionnaire (PDQ39) -secondary outcomes- and the MDS-UPDRS -secondary outcomes-. Additionally, ratings of perceived exertion (RPE) (Borg >6-20 scale) - secondary outcomes-, were recorded at the end of each PRE training session. Tests were carried out at three times: pre-test (before the training program), post-test (eight weeks after pre-tests, at the end of the training period), and four weeks after the post-test (re-test).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Investigator)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with PD AR-type and Hoehn and Yahr Scale 1-2, (H&Y)
- •Do not express any type of dementia
- •Able to stand for two min without assistance;
- •Able to walk ten metres without assistance.
- •Exclusion criteria:
- •To suffer a neurological disease other than PD.
- •Do not meet some of the inclusion criteria.
排除标准
- 未提供
结局指标
主要结局
Static posturography through the centre of pressures measurements (CoP).
时间窗: Eight weeks
次要结局
- Gait.(Eight weeks)
- The patient- perceived quality of life.(Eight weeks)
- Freezing of gait.(Eight weeks)
- The Movement Disorders Society-Unified Parkinson ́s Disease Rating Scale. (MDS-UPDRS).(Eight weeks)