Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Change of baseline pain measured by visual analogue scale (0-10) after 28 days
研究概览
简要总结
To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis
详细描述
The investigators would like to evaluate how inflammation occurs in the joints of subjects with osteoarthritis, and identify molecules and bacteria that can predict whether a patients with knee osteoarthritis will have more or less pain . Blood, urine and stool will be evaluated in the laboratory and compared to their own samples after changes in diet. This is an exploratory study, which is meant to gather preliminary data about the quick effects of changes in diet and treatment on molecules in blood/urine and bacteria in stools. These studies can provide clues to the cause of disease and might ultimately lead to new therapies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed of Knee Ostoeaarthritis
- •without changes in treatment in the last 3 months
排除标准
- •food allergies
- •pregnancy
结局指标
主要结局
Change of baseline pain measured by visual analogue scale (0-10) after 28 days
时间窗: 28 days
Change of baseline pain measured by visual analogue scale (0-10) after 28 days, being 0 no pain, and 10 the worse outcome
次要结局
未报告次要终点
研究者
Monica Guma
Associate Professor of Medicine
University of California, San Diego