Coronary Sinus diameter: Marker of Right Ventricular dysfunction in patients undergoing surgery for Tetralogy of Fallot
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To study the association between coronary sinus diameter and RV myocardial performance index.
研究概览
简要总结
The deoxygenated blood from the heart is emptied into the right atrium through the coronary sinus(CS). Available literature shows relationship between coronary venous system with multiple heart pathologies like heart failure and ischemic coronary artery disease.Coronary venous system can also be treated as buffer of RV changes.
Studies have shown that CS diameter has increased in patients with ischemic heart failure and might also be a part of cardiac remodeling process. In this study we aim to use CS diameter as a marker of RV dysfunction in children undergoing corrective surgery of tetralogy of fallot.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 6.00 Month(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •All childern between the age of 6 month and 18 year undergoing surgical repair for Tetralogy of Fallot under Cardiopulmonary Bypass.
排除标准
- •Children having Tetralogy of Fallot with associated anamoly, presence of left Superior venacava, children having pre-existing renal dysfunction, children with pre-existing LV dysfunction and tricuspid regurgitation, children having a history of previous cardiac surgery.
结局指标
主要结局
To study the association between coronary sinus diameter and RV myocardial performance index.
时间窗: preoperative, 24 hours, 48 hours post surgery.
次要结局
- to study the relationship between RV filling pressure and coronary sinus diameter. to study the association between RV area and coronary sinus diameter.(preoperative, 24 hours, 48 hours post surgery)
研究者
Dr Jigisha Pujara
UN Mehta Institute of Cardiology and Research Centre.