High Flow Nasal Cannula Therapy for Infants With Bronchiolitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 111
- 试验地点
- 8
- 主要终点
- PEWS (Pediatric Early Warning Score) (in points 0-28)
研究概览
简要总结
In this multi-centre randomized controlled trial the investigators compare the effect on dyspnoea severity of oxgen delivery through High Flow Nasal cannula with Low Flow Nasal Prongs in children < 2 years of age hospitalised for bronchiolitis with moderate-severe dyspnoea.
详细描述
In this multi-centre randomized controlled trial the investigators compare the effect on dyspnoea severity of oxgen delivery through High Flow Nasal Cannula with Low Flow Nasal Prongs in children < 2 years of age hospitalised for bronchiolitis with moderate-severe dyspnoea. The study will take place on the pediatric (Non intensive care) units of 5 different hospitals in the Netherlands.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 1 Week 至 24 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •bronchiolitis PEWS (Pediatric Early Warning Score 0-28) >= 6 oxygen saturation < 92%
排除标准
- •chronic lung disease hemodynamic significant heart disease syndromal disease facial abnormalities
结局指标
主要结局
PEWS (Pediatric Early Warning Score) (in points 0-28)
时间窗: 24 hours
Sustained reduction in PEWS \>= 2 points within 24 hours (min 0- max 28 points)
次要结局
- Comfort (in points 0-10)(24 hours)
- duration of hospitalisation in days(15 days)
- admission to PICU (Pediatric Intensive Care Unit) (yes or no)(5 days)
- ability to feed (yes or no)(5 days)