NCT00200226已完成3 期
Oral Misoprostol Before Endometrial Biopsy
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 2
- 主要终点
- pain/discomfort of endometrial biopsy
研究概览
简要总结
An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus. Sometimes there may be discomfort with this procedure especially if the cervix is not dilated or opened. Previous research has suggested that taking a drug called misoprostol may help the cervix to start to dilate or open. This study will see if misoprostol will help open the cervix for an endometrial biopsy, to lessen the discomfort and make the biopsy easier to perform.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •women 19 years and older
- •planned endometrial biopsy
排除标准
- •known hypersensitivity or allery to prostaglandins
- •seizure disorder
- •liver disease
- •known abnormal liver function tests
- •pregnancy
研究组 & 干预措施
1
Placebo Comparator
Vitamin B6
干预措施: vitamin B6 (Drug)
2
Active Comparator
misoprostol
干预措施: misoprostol (Drug)
结局指标
主要结局
pain/discomfort of endometrial biopsy
时间窗: during procedure
次要结局
- ease of performing biopsy(during procedure)
- success of obtaining biopsy(during procedure)
- potential side effects(time study drug taken until procedure)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
3 期
Optimum Misoprostol Dose Prior to Office HysteroscopyAbnormal Uterine and Vaginal Bleeding, UnspecifiedRecurrent AbortionInfertilityNCT01612065Cairo University132
尚未招募
4 期
se of misoprostol before hyteroscopy exam to evaluate intrauterine in postmenopausal women.Endometrial polyps. Postmenopausal bleeding.N95.0RBR-9py4kdniversidade Estadual de Campinas - UNICAMP
撤回
3 期
Vaginal Misoprostol for Cervical Ripening Prior to Endometrial BiopsyEndometrial BiopsyCervical RipeningMenorrhagiaNCT00953641University of Saskatchewan
已完成
不适用
The Compatibility of Preoperative Endometrial Biopsies With Postoperative Final Pathology in Endometrial CancerEndometrial Cancer StageGynecologic CancerNCT04917341Batman Training and Research Hospital960
Unknown
不适用
Vaginal Misoprostol to Improve the Neonatal Respiratory OutcomeNeonatal Respiratory DistressNCT03239327Assiut University292