Vascular Risk Progression in Normal and Diabetes Control Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Carotid intima media measurement change
研究概览
简要总结
The purpose of this study is to look at the progression of cardiovascular disease (CVD) in normal control individuals and in patients with controlled diabetes.
详细描述
Cardiovascular disease remains the greatest cause of mortality in people with diabetes mellitus. This observation study will evaluate non-traditional risk factors for their contributions to vascular disease progression as determined by carotid intima media thickness and history of vascular disease events over 1 year. This study requires annual checks of blood, urine, history, and carotid ultrasound for carotid intimal medical thickness.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •19 years old or more and willing to return for annual testing for 2 years.
- •Those with Diabetes need to have the condition for at least 5 years.
- •Normal controls need to have no diabetes, kidney disease, or chronic disease.
排除标准
- •Estimated GFR <60 (mL/min/1.73m2)
- •Any condition that would change weight dramatically in the near future such as malabsorption, pregnancy, malignancy
- •For Normal: BMI>30, BP > 140/90 , LDL >
- •For Diabetes: BP> 135/85, A1C> 8%. LDL > 100.
结局指标
主要结局
Carotid intima media measurement change
时间窗: 2 years
To describe carotid intima media measurement change over 2 year period in normal individuals compared to individuals with well controlled diabetes
次要结局
未报告次要终点