Use of Point-of-Care Ultrasound (POCUS) for the Diagnosis of Acute Chest Syndrome in Patients With Sickle Cell Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 2
- 主要终点
- Participation rate
研究概览
简要总结
Feasibility and reliability of ultrasound in the inpatient hematology setting.
详细描述
Acute chest syndrome (ACS) is a complication of sickle cell disease where individuals have symptoms of fever, low oxygen levels or difficulty breathing in the setting of a new lung finding on chest x-ray. Chest x-ray is a useful tool to identify it but has some side effects. The investigators think ultrasound will be an equally feasible, reliable tool and minimize some of the side effects associated with chest x-ray. Ultrasound is a non-invasive was to obtain an image that does not require radiation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- — 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 0-25 years old
- •Diagnosis: Patients with a documented diagnosis of sickle cell disease (any genotype)
- •Disposition: Hospitalized for a SCD-related complication (e.g. VOC)
排除标准
- •Patient is considered hemodynamically unstable to undergo consent and study procedures
- •Already has diagnosis of ACS prior to admission to inpatient unit
- •POCUS operator not available
研究组 & 干预措施
Ultrasound
Ultrasound days 1, 3, and 5 of hospitalization
干预措施: Point of Care Ultrasound (Device)
结局指标
主要结局
Participation rate
时间窗: Up to 5 days
Percentage of patients who are approached for study who agree to be on study
Retention rate
时间窗: Up to 5 days
Percentage of patients who remain on study
Duration of exam
时间窗: Up to 5 days
Time taken to complete POCUS examination
Acceptability of POCUS by the medical team (physicians and nursing)
时间窗: Up to 5 days
Acceptability measured using a 5-point Likert Scale (Strongly Agree to Strongly Disagree) regarding use of POCUS in inpatient setting.
次要结局
- Reliability of point of care ultrasound (POCUS) compared to standard of care (Chest X-ray)(Up to 5 days)
研究者
Seethal Jacob, MD, MS
Associate Professor of Pediatrics
Indiana University