A multicenter study on the efficacy and influencing factors of Insect Compound Particle in the treatment of MMR related stage III colorectal cancer

Shanghai Municipal Hospital of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•(1) According to the above diagnostic criteria, stage III colorectal cancer was diagnosed;
•(2) They agreed to accept radical operation, and were clinically diagnosed as tn1-2m0 after consultation, physical examination, laboratory examination and imaging examination;
•(3) Agree to collect colorectal cancer tissue samples, and agreed to carry out pathological test, MMR, RAS, malta1, NF2 gene detection and Merlin protein expression;
•(4) We agreed to collect peripheral blood for metabonomics analysis;
•(5) Aged >=18 years old;
•(6) The ECoG of the patients with an estimated survival time of more than 6 months was less than 2;
•(7) They agreed to be followed up;
•(8) The follow-up and clinical data were complete;
•(9) Those who voluntarily sign informed consent.

•(1) Complicated with other primary malignant tumor;
•(2) Complicated with serious heart, brain, liver, kidney disease, electrolyte abnormality or mental illness;
•(3) Patients who are allergic to the drugs used in this study or their ingredients;
•(4) Pregnancy, lactation or planned pregnancy;
•(5) With serious or uncontrollable infections;
•(6) Those who took other traditional Chinese medicine or participated in other clinical trials in recent 2 weeks.

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