CTRI/2024/06/068660尚未招募3 期
Effect of prophylactic nebulization of Colistin versus Amikacin on the incidence of ventilator-associated pneumonia in an intensive care unit setting with prevalent multidrug-resistant bacteria: A prospective double-blind randomized placebo-controlled trial. - NI
Department of Anaesthesiology and Critical Care0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Patients requiring mechanical ventilation for more than 72 hours.
排除标准
- •Grossly purulent sputum or pneumonia on admission; new and persistent infiltrates on chest radiography within 48 hours from admission.
- •Severe chronic obstructive pulmonary disease (COPD) or preexisting lung disease requiring long-term inhalation drug therapy.
- •Long-term therapy with corticosteroids or immunosuppressive drugs, human immunodeficiency virus infection, cancer.
- •Colonization or infection with a strain resistant to colistin and amikacin on admission.
- •Acute kidney injury on the day of inclusion. Patients undergoing renal replacement therapy or for whom a decision had been made to initiate renal replacement therapy can be included whatever the KDIGO stage.
- •Chronic kidney failure.
- •Pregnancy and breastfeeding women.
- •Allergy to colistin or amikacin.
- •Myasthenia gravis.
研究者
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