Optical Coherence Tomography Angiography Analysis After Childhood Lensectomy
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Area of foveal avascular zone
研究概览
简要总结
The aim of this study is to quantify and compare the foveal avascular zone (FAZ), the parafoveal and foveal vessel density of superficial (SCP) and deep capillary plexus (DCP) and retinal thickness in deprivation amblyopic eyes, fellow non-amblyopic eyes, and age-matched normal eyes, using optical coherence tomography angiography (OCTA). The FAZ, parafoveal and foveal SCP and DCP, and retinal thickness were measured in normal controls and at least 3 months postoperatively in children with unilateral cataract and compared between groups after adjusting for axial length and spherical equivalents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 3 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •children after cataract surgery and healthy volunteers
排除标准
- •presence of corneal opacity preventing detailed imaging
- •nystagmus
- •retinal disease,
- •persistent fetal vasculature
- •intraocular inflammation,
- •vitreoretinal surgery
- •premature birth
- •neurologic disease
- •systemic disease that could alter microvasculature (including diabetes, hypertension, cardiovascular disease and renal disease)
结局指标
主要结局
Area of foveal avascular zone
时间窗: up to 36 months
Area of foveal avascular zone in square microns
Foveal retinal thickness
时间窗: up to 36 months
Foveal retinal thickness in microns
次要结局
未报告次要终点
研究者
Yune Zhao
Director of Cataract Department
Wenzhou Medical University