A Prospective Observational Study of Transcranial Doppler Ultrasound in the Assessment of Cerebral Blood Flow After Polyetheretherketone Cranioplasty
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- transcranial doppler ultrasonography parameters before and after cranioplasty
研究概览
简要总结
Polyetheretherketone has become one of the most important material choices for cranioplasty surgery. It has been shown that conventional ultrasound can be performed through the polyetheretherketone material for the examination of brain tissue and ventricular morphology. Transcranial doppler ultrasound can obtain good images of cerebral hemodynamic parameters in patients through polyetheretherketone-covered temporal window. This trial is a clinical prospective observational study in which cases treated with polyetheretherketone cranioplasty, and transcranial doppler ultrasonography is performed preoperatively and 10 days postoperatively, and data were collected mainly including bilateral hemodynamic parameters of middle cerebral artery(MCA), terminal internal carotid artery(TICA), (anterior communicating artery)ACA, and posterior cerebral artery(PCA) (Vs, Vd, Vm, PI index, RI index) from temporal window.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age of 18 years or older;
- •Proposed polyetheretherketone cranioplasty;
- •Incomplete cranial bone in the lateral temporal window;
- •Signed informed consent for surgery and informed consent for research.
排除标准
- •Although cranioplasty is proposed, the cranial bone in the temporal region is intact.
结局指标
主要结局
transcranial doppler ultrasonography parameters before and after cranioplasty
时间窗: 6 months
transcranial doppler ultrasonography's hemodynamic parameters: Pulse Index(PI) of middle cerebral artery(MCA), terminal internal carotid artery(TICA), anterior communicating artery(ACA), and posterior cerebral artery(PCA) from bilateral temporal window before and after polyetheretherketone cranioplasty. PI=(Vs - Vd )/ Vm。
次要结局
未报告次要终点
研究者
Junfeng Feng
Chief Director of Brain Injury Center
RenJi Hospital
