Outcome Predictors in Children With Acute Disseminated Encephalomyelitis at Assuit University Children Hospital
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 25
- 主要终点
- Proportion of Patients Achieving Complete Recovery Assessed by the Modified Rankin Scale (mRS)
研究概览
简要总结
The aim of the present study is to determine outcome predictors in children who were diagnosed as acute disseminated encephalomyelitis (ADEM).
详细描述
Outcome predictors in children with Acute Disseminated Encephalomyelitis
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Months 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children aged from 6 months old to 18 years.
- •Presence of clinical signs of acute encephalopathy with multifocal neurological deficits.
- •MRI findings suggestive of demyelinating lesions.
排除标准
- •Pediatric patients diagnosed who were as multiple sclerosis.
- •Pediatric patients with clinical signs and radiological findings suggestive of neuromyelitis optica spectrum disorder.
- •Pediatric patients with infectious encephalitis.
- •Pediatric patients with metabolic or genetic neurological disorders
结局指标
主要结局
Proportion of Patients Achieving Complete Recovery Assessed by the Modified Rankin Scale (mRS)
时间窗: 6 months
Functional disability and recovery are assessed using the Modified Rankin Scale (mRS), a validated 7-point scale ranging from 0 to 6. A score of 0 indicates no symptoms at all, 5 indicates severe disability (bedridden, requiring constant care), and 6 indicates death. For this study, complete recovery is defined as achieving an mRS score of 0 or 1 (no significant disability). This measure reports the percentage of participants who meet this specific recovery criteria.
次要结局
- Incidence of Disease Relapse(up to 12 months)
- Incidence of Residual Neurological Deficits(up to 12 months)
研究者
Norma Samy Gergis
Resident at Assiut University Hospitals
Assiut University