ACTRN12615001233516已完成不适用
Randomized trial of doxycycline and Microdacyn versus standard care for prevention of intra-operative wound contamination and postoperative infection in clean elective surgical procedures
Mr Philip Knight, Orthopaedic Surgeon,0 个研究点目标入组 200 人开始时间: 2015年11月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
入排标准
- 年龄范围
- 16 Years 至 o limit（—）
- 性别
- All
入选标准
- •Able to provide informed consent; willingness to take part.
- •To undergo a clean procedure in Orthopaedic (e.g. joint prosthesis, arthroscopy, tendon repair, internal fixation, laminectomy, spinal fusion) or pacemaker insertion surgery
- •During the period 9 November 2015 to 10 February 2016 (for shoulder procedures at Manuka St Hospital during the extended period of 9 November 2015 to 9 November 2016).
排除标准
- •Pregnancy or breastfeeding.
- •Past adverse reaction to Microdacyn, doxycycline, minicycline tetracycline, cephlasporins , severe penecillin reactions, or chloxhexadine.
- •Previous Clostridium difficile colitis.
- •Suspected current infection on the overlying skin or in the deep tissues at the operation site.
- •At least one dose of a systemic antibiotic in the 4 days before the start of the trial.
- •The operation site is covered by plaster of Paris or a dressing during the 3 days before the operation.
研究者
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