Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- duration of airleak
研究概览
简要总结
Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases.
Management of symptomatic malignant pleural effusion remains to be a point of debate. Data available from literature shows conflicting results lacking high quality evidence which necsscitates further research work. Options differs to include chemical pleurodesis using medical or surgical talc poudrage or slurry. Surgical intervention with abrasion pleurodesis or pleurectomy using VATS approach has been used in many studies. Using indwelling pleural catheters (IPCs) has also proved comparable efficacy at many clinical trials. In this study we want to help answering this question so that we can add to the current knowledge aiming to offer the best care for those patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 5 Years 至 90 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1-patients with symptomatic malignant pleural effusion. 2- symptomatic patients with shortness of breath. 3-Lung can be fully expanded.
排除标准
- •Patients with non symptomatic malignant pleural effusion
- •Pleural symphysis with no potentiality for re-expansion
- •Patients managed surgically through open thoracotomy.
- •Pleural effusion due to causes other than malignancy
- •Loculated malignant effusion judged by chest ultrasound
- •Trapped lung due to malignant pleural effusion assessed by multislice CT chest.,
- •.Refusal to share the research project and not to sign the consent.
结局指标
主要结局
duration of airleak
时间窗: 3 months postoperative
duration in days
Total hospital stay
时间窗: 3 months postoperative
duration of hospital stay in days
次要结局
- Status of performance(3 months)
- Failure of management(3 months)
- mortality('3 months)
研究者
Kareem Ahmed Hosny
Principle investigator
Assiut University