IRCT20120520009801N6尚未招募3 期
The effect of dextromethorphan on the severity of symptoms in patients with obsessive-compulsive disorder: A double blinded, randomized clinical trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 72
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •OCD patients who have been treated with high doses of SSRI for at least 8 weeks but have a Y-BOCS index score higher than 15. (High doses of SSRI includ: Sertraline 200mg/day, Paroxetine 60mg/day, Fluoxetine 80mg/day and Fluvoxamine mg/day)
- •subjects aged 18 to 60 years
- •Obtaining the patient's informed consent
排除标准
- •Pregnancy or breastfeeding
- •Using serotonergic drugs other than SSRIs
- •Use of NMDA receptor antagonists other than dextromethorphan and memantine
- •Psychotic and bipolar disorders (based on DSM-5 criteria)
- •Liver dysfunction (LFT> 3ULN)
- •Kidney dysfunction (GFR <60 ml / kg / min)
- •Thyroid Disorders (Based on Thyroid Function Test)
- •History of seizures
研究者
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