NCT00002216已完成不适用
A Comparison of a Four-Drug Regimen Comprised of 141W94, 1592U89, and Combivir With a Three-Drug Regimen Comprised of Nelfinavir and Combivir in Antiretroviral-Naive HIV-Infected Patients.
Glaxo Wellcome2 个研究点 分布在 1 个国家开始时间: 2001年8月31日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 试验地点
- 2
研究概览
简要总结
The purpose of this study is to compare 2 combination drug therapies in HIV-infected patients who have never received anti-HIV treatment.
详细描述
In this open-label study antiretroviral-naive patients are randomized to one of two drug regimens:
Arm I: 141W94 (amprenavir), 1592U89 (abacavir), and Combivir (3TC/AZT tablet). Arm II: Nelfinavir and Combivir.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have:
- •CD4 count >
- •HIV RNA > 5,
- •No active AIDS (excluding CD4 count < 200).
- •Ability to comply with dosing schedule and protocol evaluations.
- •Prior Medication:
- •3TC or any protease inhibitor, if < 1 week of therapy.
- •Other nucleoside analogs, if < 4 weeks of therapy.
排除标准
- •Co-existing Condition:
- •Patients with any of the following symptoms or conditions are excluded:
- •Active AIDS (not including CD4 count < 200).
- •Malabsorption syndrome affecting drug absorption.
- •Concurrent Medication:
- •Enrollment in any other investigational drug protocol.
- •Prior Medication:
- •Non-nucleoside reverse transcriptase inhibitors.
研究者
研究点 (2)
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