ISRCTN06022197已完成不适用
A pilot study of a randomised controlled trial of antipsychotic medication in comparison to cognitive behaviour therapy and a combined treatment in adults with psychosis
Greater Manchester West Mental Health NHS Foundation Trust (UK)0 个研究点目标入组 75 人开始时间: 2014年3月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 75
研究概览
简要总结
2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/29605187
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Current inclusion criteria as of 25/07/2014:
- •1. In contact with mental health care services (under the care of a consultant)
- •2. Either meet ICD-10 criteria for schizophrenia, schizoaffective disorder or delusional disorder or meet entry criteria for an Early Intervention for Psychosis service (operationally defined using PANSS) in order to allow for diagnostic uncertainty in early phases of psychosis
- •3. Aged 16+
- •4. Competent and willing to provide written, informed consent
- •5. Score at least 4 on PANSS delusions or hallucinations or at least 5 on Suspiciousness/Grandiosity
- •6. Help seeking
- •Previous inclusion criteria:
- •1. Aged 18+
- •2. In contact with mental health services
- •3. Competent to provide written, informed consent.
- •4. Either meet ICD-10 criteria for schizophrenia, schizoaffective disorder or delusional disorder or meet entry criteria for an Early Intervention for Psychosis service (operationally defined using PANSS) in order to allow for diagnostic uncertainty in early phases of psychosis
- •5. Score at least 4 on PANSS delusions or hallucinations or at least 5 on suspiciousness/grandiosity
- •6. Help seeking
排除标准
- •Current exclusion criteria as of 25/07/2014:
- •1. Primary diagnosis of alcohol/substance misuse
- •2. Moderate or severe learning disability
- •3. Score 5+ on PANSS conceptual disorganisation
- •4. Non-English speaking
- •5. Current receipt of structured CBT from a qualified psychologist in accordance with NICE guideline recommendations (as opposed to more generic psychosocial interventions) OR receipt of antipsychotics, OR receipt of either within the past 3 months.
- •6. Immediate risk to self or others
- •7. Organic Impairment
- •Previous exclusion criteria:
- •1. Primary diagnosis of alcohol/substance dependence
- •2. Moderate or severe learning disability
- •3. Score 5+ on PANSS conceptual disorganisation
- •4. Non-English speaking
- •5. Current receipt of structured CBT or APs, or receipt within the last 3 months
- •6. Inpatient
- •7. Immediate risk to self or others
- •8. Organic Impairment
研究者
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