Effect of Vitamin D Levels on Postoperative Pain and Narcotic Analgesia in Patients With Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- preoperative Vitamin D Level and postoperative pain in patients to undergo laparoscopic cholecystectomy operation
研究概览
简要总结
The deficiency of vitamin D is common in patients with gastrointestinal system disorders.
Vitamin D has been associated with chronic non-specific musculoskeletal pain and migraines due to anti-inflammatory effects.
This prospective observational study will undergo elective laparoscopic cholecystectomy surgery between 18 and 65 years, is planned to participate in ASA (American Society of Anesthesiologists) 1-3, 90 volunteer patients.
In preoperative evaluation, the remaining 3 ml of blood was centrifuged from the routine received blood to determine the level of vitamin D will be kept.
Postoperative will be applied to patient controlled analgesia to all patients for 24 hours.
To determine the level of postoperative pain, the visual analog scale (VAS) will be used in the clock unit and at the service 6, 12 and 24 hours.
In this study, the investigators aimed to test the hypothesis of relation to pain and opioid consumption in acute postoperative (24 hours) of perioperative low-vitamin D.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Volunteer,
- •Between the Ages Of 18-65,
- •Least Primary School Graduate,
- •Not Using Drugs That May Affect Cognitive Functions,
- •Non-Alcohol Substance Use,
- •Patients Without Psychiatric and Neurological Disease.
排除标准
- •Those with known psychiatric disease and drugs,
- •Those with an important cardiovascular or central nervous system disease,
- •Patients with pain syndromes or routinely using opioid.
- •Very urgent patients
结局指标
主要结局
preoperative Vitamin D Level and postoperative pain in patients to undergo laparoscopic cholecystectomy operation
时间窗: 6 months
Correlations of preoperative Vitamin D Level between postoperative pain in patients undergoing laparoscopic cholecystectomy.to undergo laparoscopic cholecystectomy operation
次要结局
- preoperative Vitamin D Level and opioid analgesic consumption(6 months)
研究者
Ökkeş Hakan Miniksar
Assistant Professor
Bozok University