跳至主要内容
临床试验/NCT04098159
NCT04098159Unknown不适用

Role of Regular Surveillance on Maintenance of Patency of an Arteriovenous Access

Assiut University0 个研究点目标入组 200 人开始时间: 2019年11月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
200
主要终点
Number, type and technical success rate for elective interventions

研究概览

简要总结

Chronic Kidney disease (CKD) is a worldwide public health problem that classified into five stages (1). End stage renal disease (CDK stage 5) patients require a well-functioning vascular access (VA) for successful hemodialysis treatment (2). Types of VA include arteriovenous fistulae (AVFs) and arteriovenous grafts (AVGs). A vascular access is liable to early or late complications, and ultimately access failure. A meta-analysis showed that a 17% mean early access failure However recent studies have shown higher failure rates of up to 46%, with one year patencies between 52% to 83% (3). Low VA flow, thrombosis and loss of patency may result in under-dialysis that leads to increased morbidity, mortality and healthcare expenditure (4). In the majority of VAs, stenoses develop over variable intervals causing VA thrombosis and failure (5). If early detected and corrected, VA function and patency can be preserved and under-dialysis can be minimized or avoided. The aim of this study is to find out the role of periodic surveillance of VA in the detection of VA dysfunction and correctable lesions that may necessitate pre-emptive interventions to maintain VA patency and prevent VA loss

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • ESRD Patients have functioning or failing VAs (AVFs or AVGs).

排除标准

  • ESRD patients have infected or failed VAs .
  • patientrefusal .

研究组 & 干预措施

ESRD Patients have functioning or failing VAs (AVFs or AVGs).

Experimental

干预措施: duplex ultrasound (Device)

结局指标

主要结局

Number, type and technical success rate for elective interventions

时间窗: within one year of creation of the VA

次要结局

  • secondary patency rate of the Arteriovenous Access after elective intervention(within one year of creation of the VA)
  • number , type of complication that resulted from elective interventions(within one year of creation of the VA)
  • primary patency rate of newly created Arteriovenous Access in assiut governorate(within one year of creation of the VA)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmed Mohammed Rashed

resident of vascular surgery

Assiut University

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