A Comprehensive Observational Study on the Determinants of Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 15,000
- 试验地点
- 1
- 主要终点
- Incidence of POAF
研究概览
简要总结
This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.
详细描述
Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years or older.
- •Patients who underwent CABG.
排除标准
- •Patients with a history of preoperative atrial fibrillation or other significant arrhythmias.
- •Patients who underwent other concurrent cardiac procedures (e.g., valve surgery) in addition to CABG.
- •Patients who cannot provide informed consent or lack adequate follow-up information.
结局指标
主要结局
Incidence of POAF
时间窗: During hospital stay, up to 30 days
This will be determined based on electrocardiograms (ECG) and/or relevant medical records, within 30 days post-CABG.
次要结局
- Hospital length of stay(During hospital stay, up to 30 days)
- ICU admission time(During hospital stay, up to 30 days)
- Number of participants with Stroke(During hospital stay, up to 30 days)
- Mortality(During hospital stay, up to 30 days)
研究者
Kun Hua
Deputy Chief Surgeon
Beijing Anzhen Hospital