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临床试验/ACTRN12619000237189
ACTRN12619000237189尚未招募2 期

Superior laryngeal nerve block for the treatment of chronic cough and vocal cord dysfunction (laryngeal sensory neuropathy)

Department of Otolaryngology, Head and Neck surgery, Monash Health0 个研究点目标入组 352 人开始时间: 2019年2月18日最近更新:
适应症

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
352

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Treatment
盲法
Blinded (masking used)

入排标准

年龄范围
18 Years 至 o limit(—)
性别
All

入选标准

  • No objective evidence on formal testing and/or failure of adequate treatment to more common causes of treatment:
  • Respiratory Disease:
  • - Negative Testing: CXR or CT Chest, Broncho-provocation or Broncho-dilation testing
  • - No response to an 8 week empirical trial of inhaled corticosteroid
  • Allergic Disease:
  • - Negative Testing: Negative RAST or Skin prick testing for inhaled allergens
  • - No response to an 8 week empirical trial of intranasal and/or oral medications (e.g. Steroid, and/or Anti-histamine)
  • Laryngopharyngeal and Gastro-oesophageal Reflux Disease:
  • - Negative Testing: Negative Oral Salivary pepsin assay, or 24 hour dual probe pH/impedance monitoring.
  • - No response to an 8 week empirical trial of both acid reduction and alginate treatment.

排除标准

  • Are on neuromodulator medications (ie. Tricyclic anti-depressants, SSRIs, Gabapentinoids)
  • Are on anti-tussive medications (ie Guafenasin)
  • Cannot tolerate an ‘in-office’ procedure
  • Known allergy or intolerance to bupivacaine and/or triamcinolone acetate

研究者

发起方
Department of Otolaryngology, Head and Neck surgery, Monash Health

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