ACTRN12619000237189尚未招募2 期
Superior laryngeal nerve block for the treatment of chronic cough and vocal cord dysfunction (laryngeal sensory neuropathy)
Department of Otolaryngology, Head and Neck surgery, Monash Health0 个研究点目标入组 352 人开始时间: 2019年2月18日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 352
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit(—)
- 性别
- All
入选标准
- •No objective evidence on formal testing and/or failure of adequate treatment to more common causes of treatment:
- •Respiratory Disease:
- •- Negative Testing: CXR or CT Chest, Broncho-provocation or Broncho-dilation testing
- •- No response to an 8 week empirical trial of inhaled corticosteroid
- •Allergic Disease:
- •- Negative Testing: Negative RAST or Skin prick testing for inhaled allergens
- •- No response to an 8 week empirical trial of intranasal and/or oral medications (e.g. Steroid, and/or Anti-histamine)
- •Laryngopharyngeal and Gastro-oesophageal Reflux Disease:
- •- Negative Testing: Negative Oral Salivary pepsin assay, or 24 hour dual probe pH/impedance monitoring.
- •- No response to an 8 week empirical trial of both acid reduction and alginate treatment.
排除标准
- •Are on neuromodulator medications (ie. Tricyclic anti-depressants, SSRIs, Gabapentinoids)
- •Are on anti-tussive medications (ie Guafenasin)
- •Cannot tolerate an ‘in-office’ procedure
- •Known allergy or intolerance to bupivacaine and/or triamcinolone acetate
研究者
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