Effect of 4-session Metacognitive Training in Chinese Adult Outpatients With Schizophrenia Spectrum Disorders and Major Depressive Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 113
- 试验地点
- 1
- 主要终点
- Attributional style as measured by the Internal, Personal and Situational Attributions Questionnaire (IPSAQ)
研究概览
简要总结
Psychological studies have shown that individuals tend to attribute causes of positive and negative events differently. Specifically, individuals hold an internalising or externalising bias of attribution which, in the case of particular patient groups, was found to polarize to the extreme. Such extreme attributional styles have found to have a direct impact on emotions, leading to a waning course of psychiatric disorders. This project aims to further examine the theoretical links between attributions and emotions using a transdiagnostic approach, and the effect of a 4-session process-based intervention on attributional biases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18-65 years
- •Clinical diagnosis of non-organic psychosis or major depressive disorder
- •Presentation of delusions/a moderate level of depression
排除标准
- •Clinical diagnosis of psychotic depression or depression with psychotic features
- •Primary diagnosis of substance misuse or learning disability
- •Participation of any cognitive/reasoning training program
结局指标
主要结局
Attributional style as measured by the Internal, Personal and Situational Attributions Questionnaire (IPSAQ)
时间窗: 6 months
IPSAQ consists of hypothetical scenarios. Participants are required to think of a single, most likely causal explanation to each of the hypothesized situations, and then to categorize this cause as being internal, external-personal or external-situational.
Depressive symptomatology as measured by Beck Depression Inventory - II (BDI-II) and Calgary Depression Scale (CDS)
时间窗: 6 months
Beck Depression Inventory - II (BDI-II) is a 21-item self-report inventory that assesses symptoms of depression. Scores can range from 0 to 63, with higher scores reflecting greater symptom severity. Calgary Depression Scale (CDS) is a nine-item structured interview scale that assesses depressive symptoms in patients with schizophrenia.
Conviction of beliefs as measured by the Psychotic Symptom Rating Scale (PSYRATS)
时间窗: 6 months
The Psychotic Symptom Rating Scale (PSYRATS) is a 17-item semi-structured interview measuring the severity of multiple dimensions of auditory hallucinations and delusions, including conviction and duration.
Belief flexibility as measured by Maudsley Assessment of Delusions Schedule (MADS) and the BADE task
时间窗: 6 months
Maudsley Assessment of Delusions Schedule (MADS) is a standardised interview assessment that records whether participants could consider possibility of being mistaken (PM) about their delusional experience, any possible alternative explanations for the experience (EoE), and their reaction to hypothetical contradiction (RTHC). BADE task is an experimental design for measuring participants' bias against disconfirmatory evidence.
Psychotic symptomatology as measured by Positive and Negative Syndrome Scale (PANSS)
时间窗: 6 months
Positive and Negative Syndrome Scale (PANSS) is an interview-based assessment of the severity of symptoms associated with schizophrenia, including positive, negative, and general psychopathology.
State-trait personality as measured by the State-Trait Personality Inventory (STPI)
时间窗: 6 months
State-Trait Personality Inventory (STPI) consists of 8 self-report scales, each containing 10 items covering state and trait anger, anxiety, curiosity and depression.
次要结局
- Severity of generalized anxiety disorder as measured by Generalised Anxiety Disorder 7 (GAD-7)(6 months)
- Cognitive capacity as measured by the Chinese version of the Wechsler Adult Intelligence Scale - III (WAIS-III)(Baseline)
研究者
Suzanne Ho-wai So
Assistant Professor
Chinese University of Hong Kong