TIFU: A Non-Interventional, Descriptive Cohort Study to Describe the Use of Ticagrelor in Patients With Acute Coronary Syndrome (TIFU: Ticagrelor in Fuwai Hospital)
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Number of participants with switching between clopidogrel and ticagrelor
研究概览
简要总结
This is a single-arm non-interventional cohort study. This study is to describe the contemporary use of ticagrelor in a "real-world" setting, to reflect its acceptance and patients' compliance, and to observe its one-year safety in patients with acute coronary syndrome in Fuwai Hospital.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Established diagnosis of acute coronary syndrome
- •The use of ticagrelor in hospital
- •agree to join this clinical trial and sign informed consent
排除标准
- •Life-expectancy <1 year
- •Dialysis required
结局指标
主要结局
Number of participants with switching between clopidogrel and ticagrelor
时间窗: 12 months
Number of participants with switching between clopidogrel and ticagrelor without a reloading dose
时间窗: 12 months
Number of Participants with discontinuation of P2Y12 receptor antagonist
时间窗: 12 months
Number of Participants with ticagrelor combined with other anticoagulants
时间窗: 12 months
次要结局
- Cardiovascular Mortality, Myocardial Infarction(MI), Ischemic Stoke(12 months)
- Number of bleeding event will be recorded (defined in accordance with PLATO definition)(12 months)
研究者
Hongbing Yan
The deputy director of Center of Coronary Heart Disease and Center of Chest Pain
Chinese Academy of Medical Sciences, Fuwai Hospital