Is Eovist Suitable for Arterial-Phase MR Imaging of Liver
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 198
- 试验地点
- 2
- 主要终点
- Scanning artifacts on MRI with Eovist
研究概览
简要总结
To examine the quality of liver images produced when the contrast agent Eovist is used during MRI.
详细描述
Researchers will review data from the Eovist MRI and compare the scan with previous MRI exams the patient had with the same or other contrast agents.
To determine the efficacy of Eovist contrast agent in producing MRI images of the liver. We will monitor patients for any unusual symptoms (adverse events) when the contrast is given.
Patients are asked to hold their breath during an MRI scan. Eovist may interfere with the "breath hold" which could result in more breathing artifacts (based on a qualitative scale) on arterial images when the patients are given Eovist vs. other contrast agents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •You have had a scheduled MRI(magnetic resonance imaging) scan using the contrast agent EOVIST.
- •Male and females 21 years of age or older.
排除标准
- •Does not have a contraindication for MRI (e.g. cardiac pacemaker, ferromagnetic or metallic implants).
结局指标
主要结局
Scanning artifacts on MRI with Eovist
时间窗: 5 years
To qualitatively assess and score MRI images during unenhanced and contrast-enhanced motion-sensitive sequences for breathing artifacts when Eovist contrast is used versus other contrast agents. Eovist enhanced MRI scans will be compared to previous MRI scans performed with other contrast agents on the same patient that included breath holding sequences. Breathing artifacts on both scans will be evaluated using a respiratory motion score between 1 and 5.
次要结局
- Adverse events (including dyspnea)(30 min)
研究者
Hero Hussain, MD
Principal Investigator
University of Michigan