NCT01190553Unknown不适用
Maintenance Therapy of Intravenous Amantadine in Patients With Idiopathic Parkinson Disease Who Are Not Optimally Treated With Anti Parkinson Medications
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Improvement of UPDRS scores after 6 months of treatment
研究概览
简要总结
This is a pilot study for Maintenance Intravenous Treatment with AMANTADINE in patient with PARKINSON'S Disease who are not well balanced with medical treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with idiopathic Parkinson disease
- •Patients with no motor improvement under optimal treatment with anti parkinson medications
- •Patients with moderate to severe dyskinesias
- •Patients with PD with side effects who can not tolerate anti parkinson medications
排除标准
- •Patients with Parkinson syndromes, vascular parkinsonism or drug-induced parkinsonism
- •Patients with PD who developed adverse reactions to oral amantadine
- •Contraindication of amantadine treatment
研究组 & 干预措施
Treatment
Experimental
IV amantadine treatment
干预措施: Amantadine (Drug)
结局指标
主要结局
Improvement of UPDRS scores after 6 months of treatment
时间窗: 6 months
Improvement of dyskinesias score.
时间窗: 6 months
次要结局
未报告次要终点
研究者
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Unknown
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