The safety SUrvey of pneumonitis induced by the combination of platinum, pemetrexed and pembrolizumab in chemo-naive non-small cell lung cancer patient in the real-world setting. - SUSPECT study

Radiographic features at diagnosis predominantly comprised an organizing pneumonia pattern. Twelve patients experienced a worsening respiratory status during pneumonitis management, which was associated with a high mortality rate during treatment. Severe grade at pneumonitis diagnosis, diffuse alveolar damage (DAD) pattern, and disease extent in the lungs were significantly associated with worsening respiratory status.