Role of Cancer Ratio and Cancer Ratio Plus in the Differentiation Between Malignant and Tuberculous Pleural Effusions .
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 120
- 主要终点
- Diagnostic performance of Cancer Ratio and Cancer Ratio Plus in differentiating malignant from tuberculous pleural effusions
研究概览
简要总结
This prospective observational analytical study aims to assess the diagnostic value of Cancer Ratio and Cancer Ratio Plus in differentiating malignant pleural effusion from tuberculous pleural effusion. Adult patients with confirmed malignant or tuberculous pleural effusion will be recruited from the Chest Diseases Department, Sohag University Hospitals. Clinical, laboratory, and radiological data will be collected, and the diagnostic performance of both markers will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (≥18 years)
- •Patients with Malignant or tuberculous pleural effusion
- •Availability of complete pleural fluid analysis including lymphocyte percentage ,pleural fluid ADA, and Serum LDH level
排除标准
- •Patients with mixed etiology effusions (e.g., malignancy with infection)
- •Prior pleural interventions affecting fluid analysis
- •Incomplete clinical or laboratory data
研究组 & 干预措施
Malignant pleural effusion
干预措施: Cancer Ratio and Cancer Ratio Plus (Diagnostic Test)
Tuberculous pleural effusion
干预措施: Cancer Ratio and Cancer Ratio Plus (Diagnostic Test)
结局指标
主要结局
Diagnostic performance of Cancer Ratio and Cancer Ratio Plus in differentiating malignant from tuberculous pleural effusions
时间窗: through study completion, an average of 1 year.
Diagnostic performance will be assessed by the area under the receiver operating characteristic curve (AUC), sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and optimal cutoff values for differentiating malignant pleural effusion from tuberculous pleural effusion.
次要结局
- Correlation of Cancer Ratio and Cancer Ratio Plus with clinical and radiological characteristics(through study completion , an average of 1 year .)
研究者
Dina Mohamed Ahmed
Resident doctor at chest diseases department
Sohag University