Screening of COPD Patients at Risk of Complications in General Practice:
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 462
- 试验地点
- 1
- 主要终点
- diagnostic accuracy of the score
研究概览
简要总结
The objective of this study is to evaluate the diagnostic accuracy of the GLORI-COPD score in ambulatory care, to enable the screening of COPD patients at risk of complications, requiring early management
详细描述
Chronic obstructive pulmonary disease (COPD) is a chronic disease with a high prevalence in France, but which remains under-diagnosed due to the trivialization of symptoms and difficulty in accessing diagnostic investigations. It is associated with other co-morbidities, with an impact on the occurrence of complications and quality of life. Early management of the most severe patients would allow better control of these risks of complications. Our objective is to better identify patients with COPD at risk of complications in general practice, taking into account the totality of the patient, to improve their management.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥ 35 yo
- •smoker or former smoker ≥ 10 Pack Years
排除标准
- •Patients who have already been diagnosed with COPD by spirometry,
- •have a contraindication to spirometry,
- •have an estimated life expectancy of less than 5 years
- •are under protective measures
结局指标
主要结局
diagnostic accuracy of the score
时间窗: 12 months
The diagnostic accuracy of the score will be evaluated to determine the risk of pulmonary complication in patients with COPD. Sensitivity, specificity, positive predictive value and negative predictive value
次要结局
- COPD diagnosis(Baseline)
- complications(6 and 12 months)
- COPD Assessment test (CAT)(baseline, 6 and 12 months)
- death(12 months)
- ADO index (Age, Dyspnea, Obstruction)(baseline, 6 and 12 months)
- GOLD stage(baseline)
- Modified Medical Research Council Dyspnea scale score (mMRC)(baseline, 6 and 12 months)
研究者
Alexandre MALMARTEL
Academic doctor of medicine
University of Paris 5 - Rene Descartes