跳至主要内容
临床试验/CTRI/2020/08/027026
CTRI/2020/08/027026尚未招募1/2 期

A COMPARATIVE CLINICAL TRIAL EVALUATING THE THERAPEUTIC EFFECT OF LEKHANA BASTI AND TRAYUSHNADYA LOHA IN STHAULYA w.s.r. TO OBESITY

Dr Ramesh Prasad Gupta1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2020年1月12日最近更新:

试验速览

阶段
1/2 期
状态
尚未招募
发起方
入组人数
90
试验地点
1
主要终点
Complete Remission- 100% relief in the signs and symptoms

研究概览

简要总结

Sthaulya is mentionedamong santarpanajanita vyadhi in Ayurvedic texts. In Sthaulyaetiological factors mainly vitiate meda-kapha and vata get avarita by excessiveMeda.Thus if we use only aptarpaka dravya, it increases thevitiated vata. Therefore, treatment should be planned considering vitiatedvata, meda and kapha.Panchakarma is the prime tool ofAyurvedic therapies, mainly considered as shodhana therapy. Acharya Charaka quotedthat there is a chance of recurrence of disease treated by Shamana therapy butShodhana therapy cures the disease from its root and there is no chance ofrecurrence.

Lekhana basti  is mentioned by different ayurvedic texts, for the treatment of SantarpanothaVyadhi, Kaphaja Roga and Kaphavrita Vata.The word ‘Lekhana’ itselfindicates its action that is "Lekhanam Patlikaranam"-scarifying helps in reduction of fat. Sharangadhara considered Lekhana in awide sense as Deha Visoshanam, ‘Dhatun - Malan va DehsyaVishoshya Lekhayechha yat Lekhanam i.e. the process of dryingup or desiccation of all excess Dosha, Dhatu and Mala. Basti denotes karma inwhich the drugs are administered through the anal canal and it stays for acertain period of time and then they draw the waste substances from all overthe body in to the colon and eliminate them out of the body by producingmovements in the colon resulting in to the pleasant effect.

Shodanain the form of Basti karma is mentioned as unique treatment modality inSthaulya specially with the drugs which are of ushna, tikshna, Lekhana thathelp in combating Kapha and medodushti. Lekhana Basti is emphasized by all theauthors of Ayurveda as treatment procedure in Medoroga. Considering thisaspect, Lekhana is opted for this study. Lekhana basti will be preparedin the same format of Asthapana Basti.

Trayushnadyaloha is a popularly used oral medicine, mentioned in Yogaratnakaraas shamanoushadhi for Medoroga Chikitsa. The ideal shamana in the treatment of Sthaulya is usage of Vata,kaphahara, and Medohara properties. Oral administration of various drugs like Shilajatu, Triphala, Guggulu Prayoga, Madhvambu Prayoga, Gomutra Prayogaetc has been indicated. In the treatment of Sthaulya, the drug administrationfor the purpose of Karshana, should be Pragbhakta (before meal). HenceTrayushnadyaLoha the drug is with a combination of Aamalaki,Vibheetaki, Hareetaki, Shunti, Pippali, Maricha, Chavya, Chitraka, Bakuchi,Bida lavana, Audbhida lavana, Saindhava lavana and Souvarchala lavana withequal amount of Loha bhasma, that  haveushna virya and laghu, ruksha guna and are exactly opposite to the gunas ofkapha and medodhatu,  is planned toevaluate its therapeutic efficacy in sthaulya.

In spite of vigorous research workson this area with different modalities of the treatment, mankind is stillleading miserable life with this disease. It is the need of the hour to explorean effective, economic, domiciliary management for this disorder. Ayurveda emphasizesvarious treatment modalities in the treatment of Sthaulya roga that includesboth Shodhana and Shamana which are of Rukshana and Apatarpana in nature.  Thus consideringgravity of the problem and availability of effective remedy this study entitled A COMPARATIVE CLINICAL TRIAL EVALUATING theTHERAPEUTIC effECT of LEKHANA BASTI AND TRAYUSHNADYA LOHA in****sthaulya w.s.r. TO OBESITYis planned to evaluate and to compare the efficacy of Lekhana Bastiand TrayushnadyaLohain Sthaulya.

研究设计

研究类型
Interventional
分配方式
Adaptive randomization, such as minimization
盲法
Open Label

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients with classical features of Sthaulya.
  • Patients having BMI more than or equal to 30 kg/m2 Patients of either gender between the groups of 20-60 years.
  • Patients fit for Basti karma.

排除标准

  • Patients not fulfilling the inclusion criteria.
  • Patients having associated complication like cardiac diseases.
  • Patients having Sthaulya due to endocrine or genetic abnormalities Patients having fissure, fistula and hemorrhoids.

结局指标

主要结局

Complete Remission- 100% relief in the signs and symptoms

时间窗: Total Duration- 56 days

Marked Improvement- More than 75% relief in the signs and symptoms

时间窗: Total Duration- 56 days

Moderate Improvement- 50-74% relief in the signs and symptoms

时间窗: Total Duration- 56 days

Mild Improvement- 25-50% relief in signs and symptoms

时间窗: Total Duration- 56 days

次要结局

未报告次要终点

研究者

发起方
Dr Ramesh Prasad Gupta
申办方类型
Other [Ph D Research Scholar]

研究点 (1)

Loading locations...

相似试验