NCT01110369已完成不适用
A Protein Supplementation and Exercise Strategy to Promote Muscle Protein Anabolism in Frail Elderly People
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- Change in skeletal muscle mass
研究概览
简要总结
The present study is designed to investigate whether timed protein supplementation will increase skeletal muscle mass in the frail elderly population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Frail elderly individuals
- •Able to understand and perform the study procedures
排除标准
- •Type I or type II diabetes (fasted blood glucose level ≥7,0 mmol)
- •No recent history (within 2 years) of participating in any regular resistance exercise training program (general questionnaire)
- •Use of anti-coagulation medication (except of Acetyl Salicyl acid)
- •Presence of coronary heart disease (ECG)
- •Renal insufficiency (eGFR <60 mL/min/1.73 m2)
- •Allergic or sensitive for milk proteins
研究组 & 干预措施
Resistance exercise training and protein drink
Experimental
干预措施: Protein drink (Dietary Supplement)
Resistance exercise training and protein drink
Experimental
干预措施: Resistance exercise training (Other)
Resistance exercise training and placebo drink
Placebo Comparator
干预措施: Resistance exercise training (Other)
Resistance exercise training and placebo drink
Placebo Comparator
干预措施: Placebo drink (Dietary Supplement)
结局指标
主要结局
Change in skeletal muscle mass
时间窗: Baseline, 3 months and 6 months
次要结局
- Physical performance(Baseline, 3 months and 6 months)
- Blood will be collected to assess parameters related to the outcome measures(Baseline, 3 months and 6 months)
- Dietary intake(Baseline, 3 months and 6 months)
- Physical activity(Baseline, 3 months and 6 months)
- Cognitive performance(Baseline and 6 months)
- Blood pressure(Baseline, 3 months and 6 months)
研究者
Lisette de Groot
Professor
Wageningen University
研究点 (1)
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