NCT03133182已完成不适用
Association of Polypharmacy With Outcomes After Elective Noncardiac Surgery: a Population-based Cohort Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 266,499
- 主要终点
- Mortality
研究概览
简要总结
This study investigates the association of preoperative polypharmacy with outcomes and healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program
详细描述
Multilevel multivariable regression analysis will be used to investigate the adjusted association between preoperative polypharmacy and postoperative outcomes and healthcare resource utilization. Sensitivity analyses will be used to evaluate the robustness of the primary analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Intermediate to high risk elective non-cardiac surgery
- •Age >=66 on day of surgery
排除标准
- 未提供
研究组 & 干预措施
Polypharmacy
People taking >=5 unique prescription drugs in the 3 months prior to surgery
干预措施: Polypharmacy (Drug)
结局指标
主要结局
Mortality
时间窗: from day of surgery up to 90 days after surgery
death from any cause
次要结局
- Complications(From day of surgery to day of hospital discharge, up to 365 days after surgery)
- Institutional Discharge(date of surgery to date of hospital discharge, or 365 days after surgery, whichever comes first)
- Length of Stay(date of surgery to date of hospital discharge, or 365 days after surgery, whichever comes first)
- Costs of Care(date of surgery up to 90 days after surgery)
- Hospital Readmission(From the date of hospital discharge to 30 days after the date of discharge)
研究者
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