COVID-19: Early Detection of Worsening by Voice and Respiratory Pattern Characteristics
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,188
- 试验地点
- 1
- 主要终点
- Specificity of the respiratory pattern demonstrated in the COVID patients who experienced respiratory worsening
研究概览
简要总结
In some clinical forms of COVID-19, an uncontrolled hyper-inflammatory reaction known as a "cytokine storm" appears abruptly, around day 7, and is associated with rapid respiratory deterioration, requiring hospitalization in an intensive care unit (ICU).
At present, although risk factors for this severe form have been described, there are no validated criteria for determining which individual patients will develop this aggravation.
The study of respiratory sounds (amplitude, frequency, ...) has made it possible in other respiratory pathologies (e.g., chronic obstructive pulmonary disease) to predict exacerbations several days in advance.
Having a predictive respiratory pattern for worsening in COVID-19 would make it possible to anticipate the need for intensive care hospital beds, by means of a tool easily available on a mobile phone.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •French speaking
- •Affiliated to a social security system
- •Owning a mobile phone capable of accessing the COVOICE application
排除标准
- •Incapable adults
- •People deprived of their liberty
- •People under administrative or judicial supervision
- •Patients intubated or hospitalized in intensive care unit
结局指标
主要结局
Specificity of the respiratory pattern demonstrated in the COVID patients who experienced respiratory worsening
时间窗: Through study completion (36 months)
Sensitivity of the respiratory pattern demonstrated in the COVID patients who experienced respiratory worsening
时间窗: Through study completion (36 months)
次要结局
未报告次要终点