NCT00300560Unknown3 期
Efficacy and Safety of Colistin for Therapy of Infections Caused by Extended Spectrum Beta-Lactamase(ESBL) Producing Klebsiella Pneumoniae or Escherichia Coli
适应症
相关药物
试验速览
- 阶段
- 3 期
- 入组人数
- 152
- 试验地点
- 2
- 主要终点
- Clinical response
研究概览
简要总结
In patients with documented ESBL-producing E.coli and Klebsiella pneumoniae will be allocated to receive colistin or conventional antibiotic regimen.
详细描述
In patients with documented ESBL-producing E.coli and Klebsiella pneumoniae will be allocated to receive colistin or conventional antibiotic regimen.The primary outcome is clinical response and secondary outcomes are microbiological response and adverse events.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 yr.
- •Hospitalized to Siriraj Hospital
- •Infections with ESBL-producing E.coli or K.pneumoniae
- •Consent informed consent
排除标准
- •Pregnancy or lactating mother
- •Colistin allergy
- •Neurologic diseases
结局指标
主要结局
Clinical response
次要结局
- Microbiological response
研究者
研究点 (2)
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