NCT03024567已完成不适用
Effects of Increased Salt Intake on Energy Metabolism in Healthy Volunteers - a Randomized Clinical Study
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Dietary induced thermogenis (%)
研究概览
简要总结
To perform a randomized, double-blind clinical study on the effects of an increased salt intake on metabolic, cardiovascular and immunological parameters and the gut microbiota
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy men and women
- •18 - 50 years
- •Body mass index 18.5 - 29.9 kg/m2
排除标准
- •Clinically relevant heart, lung, liver, and kidney diseases
- •Current or chronic infection
- •Habitual use of probiotics or dietary supplements
- •Pregnancy, lactation
研究组 & 干预措施
Salt
Active Comparator
6 grams sodium chloride per day for 14 days
干预措施: Salt (Dietary Supplement)
Placebo
Placebo Comparator
6 grams gelatine per day for 14 days
干预措施: Placebo (Dietary Supplement)
结局指标
主要结局
Dietary induced thermogenis (%)
时间窗: 14 days
Decrease of dietary induced thermogenis after salt vs. placebo
次要结局
- Gut microbiome(14 days)
- Systolic blood pressure (mmHg)(14 days)
- Lymphocytic pro-inflammatory mediators(14 days)
研究者
Anja Maehler
Principle Investigator
Charite University, Berlin, Germany
研究点 (1)
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