Attentional Bias and Attentional Bias Modification Treatment in Obsessive-compulsive Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Percentage of reduction of attentional bias
研究概览
简要总结
Obsessive-compulsive disorder is a chronic condition. Even with proper treatment, no significant improvement is reached in about 30% to 40% of patients. Thus, the development of new treatment strategies is necessary. The attentional bias - ability to aversive stimuli in capturing the attention of an individual compared to a neutral stimulus - has been extensively studied. Already training attentional bias modification has been shown effective in reducing anxiety present in other anxiety disorders.This project aims to: 1 - generate knowledge on attentional bias in individuals with OCD through the use of a standardized protocol developed for OCD; 2 - available to the scientific community the first specific paradigm for the study of attentional bias in OCD patients, 3 - test the effectiveness of a training protocol for reversing attentional bias in individuals with OCD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •30 patients with obsessive-compulsive diagnosis according to DSM-V (with cleaning and or symmetry dimensions)
- •30 health controls
排除标准
- •doing any kind of behavioral therapy in the moment
研究组 & 干预措施
attentional bias modification, placebo
Measure of attentional bias modification treatment after 10 sessions of attentional bias modification (two arms). There are two arms with 15 OCD patients each one.
干预措施: attentional bias modification treatment (Behavioral)
attentional bias modification, active group
Measure of attentional bias modification treatment after 10 sessions of attentional bias modification (two arms).
干预措施: attentional bias modification treatment (Behavioral)
结局指标
主要结局
Percentage of reduction of attentional bias
时间窗: Patients will be followed an expected average of 7 weeks (baseline, 2 sessions per week - totalizing 5 weeks, 10 sessions and a session after end of treatment). Measures of attentional bias will be assessed in baseline, session 5 and after session 10.
次要结局
- Reduction of anxiety symptoms(Baseline, session 5 and end of treatment (after session 10) (expected average of 7 weeks))
研究者
Roseli Shavitt
MD, Phd
University of Sao Paulo