跳至主要内容
MedPath Trial logoMedPath TrialMedPath Trial Home
临床试验/NCT01966861
NCT01966861Unknown3 期

Weaning From Mechanical Ventilation Guided by Lung Ultrasound (Brazilian WEANLUS)

D'Or Institute for Research and Education2 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2016年3月1日最近更新:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
适应症

试验速览

阶段
3 期
发起方
入组人数
300
试验地点
2
主要终点
Respiratory distress requiring re-intubation or non-invasive ventilation
研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The present study aims to evaluate the impact of a weaning strategy based on identification of early signs of respiratory distress by lung ultrasound and the consequent implementation of a "clinical optimization" protocol as compared to usual care.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —（Adult, Older Adult）
性别
All
接受健康志愿者
否

入选标准

  • •Mechanically ventilated >48h

排除标准

  • •Moderate/Severe COPD
  • •Spinal cord lesion
  • •Neuromuscular disease (previous)
  • •Lung fibrosis
  • •Tracheostomy
  • •Heart failure (EF<50%)
  • •Lung/pleural cancer
  • •inadequate "window"for LUS

结局指标

主要结局

Respiratory distress requiring re-intubation or non-invasive ventilation

时间窗: 48hours

次要结局

  • Hospital Mortality(Hospital death/discharge (up to 60 days))
  • 28-day mortality(28 days)
  • Adverse events(48h)

研究者

发起方
D'Or Institute for Research and Education
申办方类型
Other
责任方
Principal Investigator
主要研究者

Jorge Salluh

MD, PhD

D'Or Institute for Research and Education

研究点 (2)

Loading locations...

相似试验

已完成
2 期
Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of ConsciousnessArtificial RespirationConsciousness DisordersWearing Off Effect
NCT00700869Assistance Publique - Hôpitaux de Paris34
已完成
不适用
Weaning From Mechanical Ventilation Guide by Assessment of Lung Tidal Distribution With EITMechanical Ventilation
NCT03118804Southeast University, China55
已完成
不适用
Assessment of weaning from mechanical ventilation in mechanically ventilated patients at Thammasat University Hospitalprotocol of weaning from mechanical ventilationfactors affecting delayed weaning and weaning failureclinical outcomes relating to weaning from invasive mechanical ventilation.weaningdelayedfailuremechanical ventilation.
TCTR20180306001Faculty of Medicine&#44; Thammasat University32
终止
不适用
Weaning From Mechanical Ventilation in Neurological PatientsNeurological Diseases or Conditions
NCT03128086Hospital General Universitario de Castellón94
已完成
不适用
Weaning From Mechanical Ventilation Comparison of Open-loop Decision Support System and Routine CareRespiration, Artificial
NCT02842944Centre Hospitalier Universitaire, Amiens29