NCT00752778终止4 期
MRI Follow-up of Macrophagic Infiltration in MS Patients Treated With Tysabri
University Hospital, Strasbourg, France6 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2008年12月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 发起方
- 入组人数
- 8
- 试验地点
- 6
- 主要终点
- Number of enhanced lesions on MRI before and after treatment. PET scan modification in brain (in enhanced lesions and in the whole brain).
研究概览
简要总结
To evaluate the diagnosis value of MRI and positon emission tomography (PET) scan for studying macrophagic infiltration and other brain modification in multiple sclerosis (MS) patients treated with Natalizumab (Tysabri).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with MS
- •Treatment with Tysabri planned
排除标准
- •Allergy to Tysabri or MRI contrast products
- •Pregnancy
结局指标
主要结局
Number of enhanced lesions on MRI before and after treatment. PET scan modification in brain (in enhanced lesions and in the whole brain).
时间窗: At baseline and after 3 months of treatment.
次要结局
- Correlation with relapses.(During the 3 months of treatment and the 3 following months.)
研究者
研究点 (6)
Loading locations...
相似试验
Unknown
不适用
PET Study in Multiple SclerosisMultiple SclerosisNCT03787446University of British Columbia9
已完成
不适用
Role of PSMA-PET/MRI for diagnosis and follow-up of focal therapy of prostate cancerC61Malignant neoplasm of prostateDRKS00022363niversitätsmedizin Mannheim, Klinik für Urologie und Urochirurgie15
招募中
1 期
rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active SurveillanceProstate AdenocarcinomaStage I Prostate Cancer AJCC v8Stage IIA Prostate Cancer AJCC v8Stage IIB Prostate Cancer AJCC v8NCT05852041Northwestern University40
已完成
不适用
Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving TherapyEarly Stage Breast CancerBreast Cancer Stage IBreast Cancer Stage IINCT02335671Dana-Farber Cancer Institute40
已完成
不适用
Evaluation of PET/MR and PET/CT Imaging for Bone Marrow LesionsDisease of the MarrowMultiple MyelomaOsteoporosisNCT01880762NYU Langone Health44