Evaluation of Periodontal health Status in Pre and Post Menopausal Females with Periodontitis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Endogenous sex steroid hormones can alter their responses to local factors such as the presence of microbial plaque and also regulate the responses of periodontal tissues as well. Hence, prophylactic precautions and early intervention of oral diseases can show promising results in maintaining good oral health for all women.
研究概览
简要总结
Periodontal disease is associated with various risk factors among which female hormonal alteration such as menopause have been found to be connected with periodontal breakdown and osteoporosis. The aim of the study will be to determine the periodontal status in pre and post menopausal females. In this study, thirty female patients aged between 40 to 60 years visiting Department of Periodontology, SPPGIDMS, Lucknow and diagnoses with periodontitis showing Probing pocket depth >5 mm and Clinical attachment level > 4mm will be included. The patients will be divided into two groups - Group 1 comprising of 15 pre menopausal female patients with chronic periodontitis and Group II comprising of 15 post menopausal females with chronic periodontitis. Oral examination and clinical parameters such as Gingival Index (GI), Plaque Index (PI), Probing pocket depth and clinical attachment level will be assessed with a UNC 15 periodontal probe. Sex hormones can alter their responses to local factors such as presence of microbial plaque and also regulate the responses of periodontal tissues. Hence early intervention of oral diseases and prophylactic measures can show promising results in maintaining good oral health for females.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Female
入选标准
- •Female patient diagnosed with chronic periodontitis
- •The sites should exhibit clinical evidence of probing pocket depth of ≥5mm and clinical attachment loss ≥3mm.
- •Age between 20 and 60 years
- •Systemically healthy patients
- •Patients with established willingness and ability to perform adequate oral hygiene.
排除标准
- •Patients who have received antibiotic therapy within the past six months
- •Pregnant and lactating patients
- •Smokers and tobacco chewers
- •Patients who demonstrate poor oral hygiene maintenance after Phase I therapy
- •Systemic illness known to affect the outcomes of periodontal therapy; such as uncontrolled diabetes mellitus, cardiac diseases, immune-compromised (e.g., HIV individuals, under radiotherapy), patients taking medications such as corticosteroids or calcium channel blockers, which are known to interfere with periodontal wound healing.
- •Patients with any known allergy to drugs.
- •Patients with gross oral pathology or tumors.
- •Patients undergoing hormone replacement therapy.
结局指标
主要结局
Endogenous sex steroid hormones can alter their responses to local factors such as the presence of microbial plaque and also regulate the responses of periodontal tissues as well. Hence, prophylactic precautions and early intervention of oral diseases can show promising results in maintaining good oral health for all women.
时间窗: first day
次要结局
- The effect of sex hormones can be reduced with regular dental examination, maintaining good oral hygiene, and hormonal replacement therapies.(first day)
研究者
Dr Tanu Sahney
Sardar Patel Post Graduate Institute of Dental and Medical Sciences